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Head-to-head record and recent meetings.
Last 12 meetings
| 22 Oct 26 | S2–0 | Liga MX · Santos Laguna home | details → |
| 31 Jan 26 | U0–4 | Liga MX · UNAM Pumas home | details → |
| 13 Jul 25 | S3–0 | Liga MX · Santos Laguna home | details → |
| 17 Apr 25 | U0–2 | Liga MX · UNAM Pumas home | details → |
| 14 Jul 24 | D1–1 | Liga MX · Santos Laguna home | details → |
| 19 Feb 24 | U0–3 | Liga MX · UNAM Pumas home | details → |
| 3 Sep 23 | S2–1 | Liga MX · Santos Laguna home | details → |
| 15 Jan 23 | S3–0 | Liga MX · Santos Laguna home | details → |
| 21 Aug 22 | S5–1 | Liga MX · UNAM Pumas home | details → |
| 3 Mar 22 | S3–2 | Liga MX · Santos Laguna home | details → |
| 5 Nov 21 | S3–0 | Liga MX · UNAM Pumas home | details → |
| 5 Mar 21 | U0–1 | Liga MX · UNAM Pumas home | details → |
Scores shown from Santos Laguna's perspective. From graded matches on record.