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Head-to-head record and recent meetings.
Last 12 meetings
| 27 Sep 26 | S1–0 | Liga MX · Santos Laguna home | details → |
| 12 Apr 26 | P2–4 | Liga MX · Pachuca home | details → |
| 9 Nov 25 | S1–0 | Liga MX · Santos Laguna home | details → |
| 21 Jan 25 | P1–2 | Liga MX · Pachuca home | details → |
| 23 Oct 24 | D1–1 | Liga MX · Santos Laguna home | details → |
| 21 Apr 24 | P0–2 | Liga MX · Santos Laguna home | details → |
| 19 Sep 23 | P2–3 | Liga MX · Pachuca home | details → |
| 7 May 23 | D4–4 | Liga MX · Pachuca home | details → |
| 10 Apr 23 | P1–4 | Liga MX · Santos Laguna home | details → |
| 3 Sep 22 | P0–2 | Liga MX · Pachuca home | details → |
| 4 Apr 22 | S3–1 | Liga MX · Santos Laguna home | details → |
| 17 Oct 21 | D1–1 | Liga MX · Pachuca home | details → |
Scores shown from Santos Laguna's perspective. From graded matches on record.